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. 2022 Aug 1;11(15):4490. doi: 10.3390/jcm11154490

Table 4.

Comparison of the models with single parameters and their double combinations adjusted for comorbidities and potential risk factors according to AIC for individual endpoints.

ICU-Admission Mechanical Ventilation Fatal Outcome
Model AIC Model AIC Model AIC
1 albumin+ALP 439.0 1 albumin 426.2 1 albumin+TBIL 455.1
2 albumin 439.2 2 albumin+ALP 426.2 2 albumin+AST 456.8
3 albumin+ALT 440.7 3 albumin+ALT 427.3 3 albumin+ALT 462.1
4 albumin+TBIL 441.0 4 albumin+AST 427.5 4 albumin 464.1
5 albumin+AST 441.2 5 albumin+TBIL 428.0 5 albumin+GGT 464.7
6 albumin+GGT 441.2 6 albumin+GGT 428.1 6 albumin+ALP 464.7
7 NLR 456.3 7 NLR 448.4 7 AST+ALT 493.2
8 ALP 469.8 8 AST 461.1 8 AST+TBIL 493.5
9 ALT 470.4 9 AST+ALP 461.5 9 NLR 497.0
10 AST 470.4 10 ALP 461.6 10 AST 497.2
11 GGT 470.5 11 ALT 461.6 11 TBIL+GGT 497.2
12 TBIL 470.6 12 GGT 461.9 12 TBIL 497.5
13 AST+ALP 470.9 13 TBIL 462.1 13 TBIL+ALT 497.7
14 ALP+GGT 470.9 14 ALP+GGT 462.4 14 AST+ALP 498.7
15 ALP+ALT 471.0 15 ALP+ALT 462.6 15 AST+GGT 499.1
16 ALP+TBIL 471.6 16 AST+TBIL 462.8 16 ALP+TBIL 499.5
17 TBIL+GGT 472.1 17 AST+GGT 463.1 17 ALP+ALT 504.6
18 AST+TBIL 472.1 18 AST+ALT 463.1 18 ALP 504.6
19 TBIL+ALT 472.2 19 ALP+TBIL 463.3 19 ALT 504.7
20 ALT+GGT 472.2 20 TBIL+GGT 463.4 20 ALT+GGT 505.8
21 ALT+AST 472.3 21 ALT+GGT 463.4 21 GGT 506.4
22 AST+GGT 472.3 22 TBIL+ALT 463.5 22 TBIL+GGT 506.5

AIC: Akaike Information Criterion; ICU: intensive care unit; AST: aspartate aminotransferase; ALT: alanine aminotransferase; GGT: gamma-glutamyltransferase; ALP: alkaline phosphatase; TBIL: total bilirubin; NLR: neutrophil-to-lymphocyte ratio.