Table 5.
The best models to predict ICU admission in COVID-19 tested on larger groups of patients.
| ICU Admission | ||||||||
|---|---|---|---|---|---|---|---|---|
| OR | 95% CI | p-Value | Sample Size n | NG |
LR
p-Value |
AIC | ||
| Variables | 25% | 75% | ||||||
| Model: albumin+ALP | 36.810 | 8.245 | 177.080 | <0.0001 | 459 | 0.292 | <0.0001 | 518.2 |
| ALP | 0.997 | 0.994 | 1.000 | 0.101 | ||||
| albumin | 0.277 | 0.176 | 0.420 | <0.0001 | ||||
| Hypertension | 1.103 | 0.675 | 1.810 | 0.694 | ||||
| Diabetes-1 | 0.243 | 0.012 | 1.570 | 0.207 | ||||
| Diabetes-2 | 1.504 | 0.824 | 2.740 | 0.182 | ||||
| Diabetes-3 | 1.881 | 0.754 | 4.650 | 0.170 | ||||
| Diabetes-4 | 2.234 | 0.588 | 8.410 | 0.228 | ||||
| Diabetes-5 | <0.001 | <0.001 | <0.001 | 0.997 | ||||
| Asthma | 1.837 | 0.579 | 5.700 | 0.290 | ||||
| COPD | 0.236 | 0.033 | 1.050 | 0.088 | ||||
| Dementia | 0.061 | 0.009 | 0.230 | <0.001 | ||||
| Stroke/TIA in patient history | 0.650 | 0.257 | 1.540 | 0.341 | ||||
| Chronic kiedney disease | 0.279 | 0.138 | 0.540 | <0.001 | ||||
| Active smoker | 0.706 | 0.192 | 2.300 | 0.576 | ||||
| Former smoker | 0.279 | 0.069 | 0.910 | 0.047 | ||||
| Myocardial infraction in patient history | 1.704 | 0.802 | 3.630 | 0.164 | ||||
| Heart failure | 0.959 | 0.473 | 1.910 | 0.905 | ||||
| Leukemia | 4.327 | 0.946 | 21.070 | 0.058 | ||||
| Solid malignant disease without metastases | 0.863 | 0.317 | 2.260 | 0.767 | ||||
| Solid malignant disease with metastases | <0.001 | <0.001 | >1000 | 0.988 | ||||
| Lymphoma | <0.001 | <0.001 | >1000 | 0.989 | ||||
| Lenght of hospital stay | 1.007 | 0.993 | 1.020 | 0.341 | ||||
| OR | 95% CI | p-Value | Sample Size n | NG |
LR
p- Value |
AIC | ||
| Variables | 25% | 75% | ||||||
| Model: albumin | 21.583 | 6.137 | 79.200 | <0.0001 | 621 | 0.276 | <0.0001 | 666 |
| albumin | 0.295 | 0.200 | 0.430 | <0.0001 | ||||
| Hypertension | 1.055 | 0.685 | 1.630 | 0.808 | ||||
| Diabetes-1 | 0.224 | 0.012 | 1.300 | 0.168 | ||||
| Diabetes-2 | 1.751 | 1.038 | 2.950 | 0.035 | ||||
| Diabetes-3 | 1.782 | 0.809 | 3.870 | 0.146 | ||||
| Diabetes-4 | 2.423 | 0.730 | 8.030 | 0.142 | ||||
| Diabetes-5 | <0.001 | <0.001 | >1000 | 0.994 | ||||
| Asthma | 1.749 | 0.708 | 4.260 | 0.218 | ||||
| COPD | 0.514 | 0.142 | 1.610 | 0.274 | ||||
| Dementia | 0.068 | 0.015 | 0.210 | <0.001 | ||||
| Stroke/TIA in patient history | 0.748 | 0.329 | 1.600 | 0.468 | ||||
| Chronic kiedney disease | 0.263 | 0.139 | 0.470 | <0.001 | ||||
| Active smoker | 0.773 | 0.268 | 2.070 | 0.618 | ||||
| Former smoker | 0.352 | 0.105 | 1.000 | 0.065 | ||||
| Myocardial infraction in patient history | 1.495 | 0.780 | 2.840 | 0.221 | ||||
| Heart failure | 0.861 | 0.467 | 1.560 | 0.625 | ||||
| Leukemia | 4.333 | 1.092 | 17.900 | 0.036 | ||||
| Solid malignant disease without metastases | 0.532 | 0.217 | 1.200 | 0.144 | ||||
| Solid malignant disease with metastases | <0.001 | <0.001 | >1000 | 0.984 | ||||
| Lymphoma | <0.001 | <0.001 | >1000 | 0.987 | ||||
| Lenght of hospital stay | 1.006 | 0.994 | 1.020 | 0.333 | ||||
OR: Odds Ratio; 95% CI: Confidence Interval; NG: Nagelkerke pseudo R2; LR: Likelihood Ratio; AIC: Akaike Information Criterion; ICU: intensive care unit; ALP: alkaline phosphatase; Diabetes-1:diabetes mellitus type 1, including LADA; Diabates-2: diabetes mellitus type 2 treated with oral medications; Diabetes-3: diabetes mellitus type 2 treated with insulin; Diabtes-4: prediabetes; Diabtes-5: gestational diabetes; COPD: chronic obstructive pulmonary disease; TIA: transient ischemic attack.