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. 2022 Aug 8;11(15):4614. doi: 10.3390/jcm11154614

Table 1.

Definition and characteristics of proposed typical PCV and POLYPOIDAL CNV.

POLYPOIDAL CNV Typical PCV
Yuzawa et al. [13] Polypoidal lesions developing at termini of CNV under the RPE Inner choroidal vessel abnormality
Yuzawa et al. [14] N = 20 (51%) N = 19 (49%)
Choroidal thickness = 212 ± 84 µm Choroidal thickness = 348 ± 91 µm
Both feeder and draining vessels are visible, and network vessels show characteristic findings of
CNV in ICGA.
Neither feeder nor draining vessels are visible, and there are few network vessels in ICGA.
GLD in ICGA = 4759 ± 1655 µm GLD in ICGA = 1798 ± 738 µm
PCV in the narrow sense
Tanaka et al. [15] N = 85 (30%) N = 202 (70%)
Significant associations with CFH I62V and ARMS2 A69S Significant association with CFH I62V but not with ARMS2 A69S
Kawamura et al. [16] N = 13 (42%) N = 18 (58%)
Choroidal thickness = 199 ± 65 µm Choroidal thickness = 288 ± 98 µm
Type 1 PCV Type 2 PCV

PCV: polypoidal choroidal vasculopathy, CNV: choroidal neovascularization, RPE: retinal pigment epithelium, ICGA: indocyanine green angiography, GLD: greatest linear dimension. Since the “polypoidal CNV” had been proposed for CNV in PCV or PCV itself and the usage of “POLYPOIDAL CNV” by Yuzawa et al. [13,14] differs from the originally used term “polypoidal CNV”, “POLYPOIDAL CNV” by Yuzawa et al. [13,14] is written in uppercase.