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. 2022 Jul 23;27(15):4707. doi: 10.3390/molecules27154707

Table 6.

α-glucosidase and α-amylase enzyme inhibition of crude and Ext+Ch NPs, Ext+PEG NPs, and Ext+LGB NPs at the highest concentrations.

Sample Concentration
(µg/mL)
% α-Glucosidase Inhibition
Mean ± SEM
IC50 (µg/mL) % α-Amylase Inhibition IC50
(µg/mL)
Mean ± SEM
Crude extract 1000 66.15 ± 0.92 120 71.16 ± 0.13 104
500 60.74 ± 0.45 64.41 ± 0.71
250 58.99 ± 0.18 60.06 ± 0.23
125 51.31 ± 0.15 54.72 ± 0.91
62.5 43.37 ± 1.02 49.67 ± 0.37
Ext+Ch NPs 1000 72.58 ± 0.84 100 79.72 ± 0.89 86
500 69.07 ± 0.98 73.22 ± 0.16
250 67.98 ± 0.64 67.02 ± 0.23
125 51.75 ± 0.56 61.97 ± 0.56
62.5 49.78 ± 1.78 54.58 ± 0.78
Ext+PEG 1000 63.15 ± 0.45 126 67.97 ± 0.09 112
500 57.45 ± 0.73 61.27 ± 0.30
250 55.04 ± 0.03 56.22 ± 0.13
125 39.69 ± 1.03 51.82 ± 0.07
62.5 37.06 ± 1.08 47.18 ± 0.15
Ext+LGB 1000 77.59 ± 0.20 83 83.37 ± 0.21 78
500 71.62 ± 0.09 76.29 ± 0.08
250 64.60 ± 0.65 71.57 ± 0.34
125 58.46 ± 0.34 68.47 ± 0.36
62.5 54.92 ± 1.34 61.88 ± 0.67
Acarbose 1000 92.11 ± 0.84 69 86.72 ± 1.14 74
500 86.13 ± 1.34 80.54 ± 0.54
250 80.47± 1.82 73.76 ± 1.02
125 76.32 ± 1.22 69.22 ± 2.02
62.5 71.18 ± 2.02 64.28 ± 1.75