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. 2022 Aug 5;11(15):4586. doi: 10.3390/jcm11154586

Table 1.

Therapies with largest proportional differences between patients with and without biologic therapy.

Therapy Class Proportion among
Biologics Patients in %
(n = 15,284)
Proportion among Non-Biologics Patients in % (n = 106,265) Prevalence Ratio (Biologics/Non-Biologics) p-Value
Calcium 12.3 3.9 3.2 <0.001
Other immunosuppressants * 33.3 11.0 3.0 <0.001
Iron 24.7 8.6 2.9 <0.001
Oral corticosteroids 71.1 26.1 2.7 <0.001
Antidiarrheal microorganisms 4.7 2.0 2.4 <0.001
Intestinal corticosteroids 64.2 33.4 1.9 <0.001
Vitamin D 20.1 10.9 1.8 <0.001
Oral fluoroquinolones 10.4 6.9 1.5 <0.001
Gastroprokinetics 6.9 4.7 1.5 <0.001
Antitussives 6.8 4.7 1.4 <0.001
PPI 54.0 41.4 1.3 <0.001

* Mainly azathioprine.