Table 1.
Effects of berbamine (BBM), bargepten (BRG), and carveol (CAR) on the expression of GSH, GST, iNOS, and LPO in the sciatic nerve. The data expressed as the mean ± SEM, n = 6. One-way ANOVA with posthoc Tukey’stest.
| Group | GSH (µmol/mg of Protein) |
GST (µmol CDNB Conjugate/min/mg of Protein) |
iNOS (µmol/mg of Protein) |
LPO (nmol/TBARS/mg of Protein) |
|---|---|---|---|---|
| Saline (10 mL/kg) | 48.22 ± 2.1 | 43.88 ± 1.5 | 34.22 ± 3.1 | 62.43 ± 1.8 |
| PTX (2 mg/kg) | 7.22 ± 1.7 ### | 10.53 ± 2.6 ### | 105.32 ± 3.2 ### | 286.66 ± 2.2 ### |
| PTX+BBM (15 mg/kg) | 30.29 ± 2.2 ** | 36.10 ± 3.4 ** | 66.21 ± 1.6 * | 112.36 ± 2.8 * |
| PTX+BRG (100 mg/kg) | 24.24 ± 2.2 ** | 29.14 ± 2.4 ** | 78.11 ± 2.2 * | 128.10 ± 1.8 * |
| PTX+CAR (20 mL/kg) | 28.14 ± 1.2 ** | 33.50 ± 1.4 ** | 56.11 ± 2.6 * | 132.16 ± 3.8 * |
* p < 0.05 and ** p < 0.01 indicate a significant difference vs. PTX, and ### p < 0.001 indicates a significant difference vs. saline.