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Concentrations of reduced glutathione (GSH) in liver tissue for the different treatments at different evaluation times. (A–C) OrP and OrE help to restore GSH levels. (D) A significant depletion of GSH is generated, the oxidative damage is severe in chronic treatment and hepatoprotectors have no effect at this point. One-way ANOVA with Tukey’s post hoc test. * p < 0.05 compared to control group, # p < 0.05 compared to TAA group.
