Receptor for advanced glycation end products |
RAGE |
Advanced glycation end products |
AGEs |
High-mobility group protein 1 |
HMGB1 |
Amyloid β-protein |
Aβ |
Soluble receptor for advanced glycation end products |
sRAGE |
Endogenous secretory soluble RAGE |
esRAGE |
Nuclear factor kappa-B |
NF-κB |
Mitogen-activated protein kinase |
MAPK |
Systemic lupus |
SLE |
Rheumatoid arthritis |
RA |
Epithelial–mesenchymal transition |
EMT |
Alzheimer’s disease |
AD |
Amyloid prebiotic protein |
APP |
Neurofibrillary tangles |
NFTs |
Macrophage colony-stimulating factor |
M-CSF |
Blood–brain barrier |
BBB |
Endoplasmic reticulum stress |
ERS |
Protein kinase R-like endoplasmic reticulum kinase |
PERK |
Eukaryotic translation initiation factor 2α |
eIF2α |
Binding protein |
BiP |
C Jun N-terminal kinase |
cJNK |
Activating transcription factor 4 |
ATF4 |
Nuclear factor E2-related factor 2 |
Nrf2 |
Kelch-like epichlorohydrin-related protein-1 |
Keap1 |
Glyoxylate 1 |
Glo1 |
Methyl glyoxal |
MGO |
Heme oxygenase 1 |
HO-1 |
Reactive oxygen species |
ROS |
Phosphatidylinositol-3-hydroxylase |
PI3K |
Protein kinase B |
AKT |
Mammalian target of rapamycin |
mTOR |
AMP-dependent protein kinase |
AMPK |