Figure 6.

Effect of inulin on the cortex expression of gene-encoding proteins involved in oxidative stress-related mechanisms. Cat encodes catalase, Gpx1 encodes glutathione peroxidase 1, Nos2 encodes inducible nitric oxide (NO) synthase, Sod1 encodes superoxide dismutase (Cu-Zn), Cox-2 encodes cyclooxygenase-2, and Sqstm1 encodes sequestosome-1 (ubiquitin-binding protein p62). The levels of mRNA were normalized to Hprt mRNA level for calculation of the relative levels of transcripts. mRNA levels are illustrated as fold change. Data are presented in box and whisker plot format (median; min. to max.). The Mann–Whitney test was used for comparison of the level of each mRNA between CTRL and INU mice.