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. 2022 Aug 7;14(15):3227. doi: 10.3390/nu14153227

Table 3.

Odds ratios (OR) and confidence intervals for associations between maintenance of depressive episodes, incidence of depression, and consumption of omega-3, alpha-linolenic acid, polyunsaturated fats (PUFA), eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), and docosapentaenoic acid (DPA) with the estimates from models 2 and 3. ELSA-Brasil Study 2008–2010 (baseline) and 2012–2014 (first follow-up visit).

Maintenance of Depressive Episodes Crude
OR (95% CI)
Model 1
OR (95% CI)
Model 2
OR (95% CI)
Omega-3 0.88 (0.73–1.03) 0.87 (0.73–1.02) 0.87 (0.70–1.03) **
Alpha-linolenic acid 0.91 (0.61–1.35) 0.91 (0.61–1.37) 0.93 (0.62–1.39)
EPA 0.36 (0.10–1.11) 0.35 (0.10–1.07) 0.35 (0.10–1.09)
DHA 0.73 (0.50–1.02) 0.71 (0.49–1.05) 0.72 (0.49–1.01) **
DPA 0.32 (0.10–1.17) 0.29 (0.07–1.10) 0.31 (0.10–1.13)
PUFA 0.98 (0.93–1.02) 0.98 (0.94–1.03) 0.98 (0.94–1.04) **
Incidence of Depressive Episodes Crude
OR (95% CI)
Model 1 1
OR (95% CI)
Model 2 1
OR (95% CI)
Omega-3 0.90 (0.82–0.98 )* 0.91 (0.82–0.98) * 0.91 (0.84–0.98) *
Alpha-linolenic acid 0.72 (0.59–0.89) * 0.73 (0.59–0.90) * 0.71 (0.59–0.91) *
EPA 0.62 (0.34–1.09) 0.67 (0.37–1.15) 0.69 (0.39–1.20)
DHA 0.87 (0.73 -1.02) ** 0.88 (0.74 -1.04) ** 0.89 (0.75 -1.05) **
DPA 0.59 (0.29–1.12) 0.62 (0.32–1.18) 0.66 (0.33–1.25)
PUFA 0.97 (0.95–1.00) ** 0.98 (0.95–1.00) ** 0.98 (0.95–1.00) **

Model 1: sex + schooling; Model 2: model 1 + nutritional status. Model 11: sex + schooling + marital status + age group; Model 21: model 11 + nutritional status + smoking + physical activity. (*) significant (**) relevant magnitudes, but with borderline significance.