Table 5.

Semen, SDF, chromatin parameters and frequency of sperm aneuploidy in the fertile and subfertile groups.

Parameters	Fertile Group	Subfertile Group	p Value
Semen parameters	(n = 44)	(n = 511)
Sperm concentration (M/mL)	82.3 ± 50.2 (16.7–263.8)	68.8 ± 67.4 (0.6–512.5)	0.006
Total sperm count (M)	288.9 ± 190.8 (21.7–767.3)	233.8 ± 217.3 (1.0–1436.2)	0.013
Progressive motility (%)	57.9 ± 9.1 (34.0–74.0)	50.0 ± 14.4 (3.0–89.0)	<0.001
Total motility (%)	66.4 ± 8.5 (46.0–82.0)	56.6 ± 14.6 (5.0–91.0)	<0.001
Morphology (%)	8.4 ± 4.2 (1.0–22.0)	5.0 ± 3.5 (0.0–18.0)	<0.001
SDF parameters	(n = 46)	(n = 501)
Total SDF (%)	10.6 ± 8.6 (1.4–54.6)	10.7 ± 8.5 (0.0–68.6)	0.976
Vital SDF (%)	1.4 ± 1.5 (0.0–6.6)	1.4 ± 2.2 (0.0–25.0)	0.508
Chromatin parameters	(n = 10)	(n = 65)
Chromatin condensation (%)	84.5 ± 7.2 (67.0–92.0)	68.0 ± 12.4 (28.9–90.0)	<0.001
Chromatin decondensation (%)	89.9 ± 2.6 (85.0–93.0)	68.0 ± 17.8 (5.4–90.2)	<0.001
Chromatin hypocondensation (%)	7.8 ± 2.6 (5.0–14.0)	9.2 ± 7.0 (1.4–54.6)	0.601
Chromatin hypercondensation (%)	2.1 ± 0.9 (1.0–4.0)	10.8 ± 7.8 (1.6–33.1)	<0.001
Frequency of sperm aneuploidy	(n = 20)	(n = 203)
Chromosome 13
Nullisomy (%)	0.11 ± 0.15	0.16 ± 0.26	0.282
Disomy (%)	0.14 ± 0.11	0.17 ± 0.30	0.294
Chromosome 18
Nullisomy (%)	0.06 ± 0.09	0.19 ± 0.42	0.061
Disomy (%)	0.12 ± 0.16	0.20 ± 0.45	0.234
Chromosome 21
Nullisomy (%)	0.08 ± 0.11	0.14 ± 0.17	0.072
Disomy (%)	0.08 ± 0.09	0.16 ± 0.35	0.605
Chromosome X/Y
Nullisomy (%)	0.30 ± 0.31	0.31 ± 0.48	0.422
Disomy XX (%)	0.15 ± 0.21	0.11 ± 0.16	0.814
Disomy XY (%)	0.10 ± 0.12	0.22 ± 0.66	0.32
Disomy YY (%)	0.07 ± 0.10	0.07 ± 0.15	0.833
Autosomal aneuploidy (%)	0.57 ± 0.34	1.03 ± 1.10	0.04
Sex aneuploidy (%)	0.61 ± 0.45	0.71 ± 0.99	0.779
Diploidy (%)	0.48 ± 0.39	1.17 ± 1.97	0.004

Data are presented as mean ± SD (range). SDF = sperm DNA fragmentation.