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. 2022 Aug 3;27(15):4950. doi: 10.3390/molecules27154950

Table 6.

MAO-A and MAO-B inhibitory activity results.

Compounds MAO-A IC50 MAO-B IC50 SI
(1) 26.3 ± 1.03 μM 153.25 ± 1.58 nM 172
selegiline 67.24 ± 1.03 μM 19.58 ± 0.83 nM 3434
iproniazide 6.55 ± 0.75 μM 7.52 ± 0.34 μM 0.87

Each IC50 value is the mean ± S.E.M. from three experiments. SI: MAO-B selectivity index = IC50 (MAO-A)/IC50 (MAO-B).