Table 4.
Glycometabolic control and therapeutic data of the patients before and after EVLCD. Continuous variables are summarized with mean and standard deviation. Categorical variation are summarized as count (N) or percentage (%).
| Before, n = 33 |
After n = 33 |
Variation | ||
|---|---|---|---|---|
| Mean (95% CI) | p * | |||
| % HbA1c | 8.3 (1.7) | 6.8 (0.8) | −1.54 (−2.17, −0.91) | <0.001 |
| HbA1c group, N (%) | - | 0.001 | ||
| <7% | 4 (12.1) | 19 (57.6) | ||
| 7 to 8% | 11 (33.3) | 13 (39.4) | ||
| 8 to 9% | 11 (33.3) | 1 (3.0) | ||
| >9% | 7 (21.2) | 0 (0.0) | ||
| Level 2 Hypoglycemia, N (%) | 18 (54.5) | 8 (24.2) | - | 0.034 |
| Severe Hypoglycemia, N (%) | 10 (30.3) | 0 (0) | - | <0.001 |
| IU Total Insulin | 36.7 (14.9) | 28.9 (9.1) | −7.7 (−11.0, −4.5) | <0.001 |
| IU/kg/day | 0.54 (0.22) | 0.42 (0.12) | −0.12 (−0.17, −0.07) | <0.001 |
| IU Rapid-acting Insulin | 18.3 (9.5) | 10.3 (6.5) | -8.0 (−10.3, −5.7) | <0.001 |
| % Rapid-acting Insulin | 49 (13) | 34 (12) | −15 (−19, −11) | <0.001 |
| IU Basal Insulin | 18.3 (8.0) | 18.6 (5.1) | 0.3 (−1.5, 2.1) | 0.760 |
| % Basal Insulin | 0.51 (0.13) | 0.66 (0.12) | 15 (11, 19) | <0.001 |
HbA1c: glycated hemoglobin; UI: unit of insulin; * paired t-test p value; McNemar’s chi-squared test p value. There were no missing data: all variables were collected for 33 subjects at two timepoints. Variations with p values below 0.05 were considered statistically significant.