Figure 21.

Representative images showing Hematoxylin and Eosin stained (H&E) (×40) sections of pancreas. (A) Control, normal pancreas showing normal islets of Langerhans in between normal pancreatic $\beta$-cells (arrow). (B) Diabetic pancreas showing ruptured and destructed islets of Langerhans with damage in $\beta$ -cells. (C) Diabetic and Metformin group pancreas showing some normal islets of Langerhans. (D) Diabetic and AgNP (5 mg/kg) mice pancreas showing some restoration in islets of Langerhans with damage in $\beta$-cells (arrow). (E) Diabetic and AgNP (10 mg/kg) pancreas showing complete restoration of islets of Langerhans.