TABLE 1.

Quantitative assessment of the average Aβ plaque deposition in the brain of 5xFAD mice.

Brain regions	Plaque burden (%)±S.D
Motor cortex
Primary Motor Cortex, M1	3.42 ± 1.27
Secondary Motor Cortex, M2	2.75 ± 0.71
Medial prefrontal cortex
Prelimbic Cortex, PrL	1.86 ± 0.69
Infralimbic Cortex, IL	1.86 ± 1.26
Orbital cortex
Lateral, LO	2.59 ± 0.83
Ventral, VO	2.52 ± 0.95
Agranular insular cortex
Ventral/Dorsal, AIV/AID	2.38 ± 1.12
Posterior, AIP	5.94 ± 0.9
Somatosensory cortex
Primary Region, S1	6.61 ± 2.82
Barrel Field, S1BF	5.88 ± 1.30
Forelimb Region, S1FL	6.40 ± 2.21
Hindlimb Region, S1HL	8.76 ± 3.58
Piriform cortex, Pir	6.94 ± 2.00
Amygdala
Basolateral, anterior part, BLA	2.99 ± 0.68
Medial, anterior, MeA	1.22 ± 0.24
Medial, posterior, MeP	2.76 ± 0.98
Medial, Me	1.82 ± 0.40
Thalamus
Posterior, Po	6.82 ± 2.78
Ventral Posterolateral, VPL	7.84 ± 3.20
Ventral Posteromedial, VPM	6.26 ± 2.20
Dorsal hippocampus
CA1 Subfield, CA1	5.56 ± 1.45
CA3 Subfield, CA3	3.69 ± 1.83
Dentate Gyrus, DG	5.16 ± 1.43
Ventral hippocampus
Dorsal Subiculum, DS	18.382 ± 0.93
CA1 Subfield, CA1	8.832 ± 2.76
CA3 Subfield, CA3	9.06 ± 2.86
Dentate Gyrus, DG	6.538 ± 2.92
Inferior colliculus
External Cortex, ECIC	5.19 ± 1.08
Retrosplenial cortex
Dysgranular, RSD	2.3 ± 0.49
Visual cortex
Primary, V1	2.68 ± 0.81
Secondary Lateral, V2L	2.70 ± 0.55
Secondary Mediolateral and Mediomedial Area, V2ML+V2MM	2.29 ± 0.60
Auditory cortex
Primary, Au1	2.18 ± 0.66
Dorsal, AuD	1.99 ± 0.63
Ventral, AuV	1.99 ± 0.53
Temporal association cortex, TeA	1.62 ± 0.37

The plaque burden was measured using the ImageJ threshold method.