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Effect of resveratrol on nutrient sensing systems in the elderly patients with type 2 diabetes mellitus. (A) Activity of glucose-6-phosphatase in the elderly patients with type 2 diabetes mellitus after treatment with resveratrol or placebo. Resveratrol-activated nutrient sensing system molecules AMPK (B), SIRTs (C), and mTOR (D). AMPK = AMP-activated kinase, mTOR = mammalian/mechanistic target of rapamycin, SIRTs = sirtuins.
