Table 3.
Reported pregnancy outcomes in the 7 days following a first dose COVID-19 vaccination in vaccinated pregnant women and unvaccinated pregnant controls
| Control (n=339) | Any mRNA (n=5597) | BNT162b2 (n=3414) | mRNA-1273 (n=2183) | ||
|---|---|---|---|---|---|
| Miscarriage or still birth | |||||
| Overall | 7 (2·1%) | 83 (1·5%) | 51 (1·5%) | 32 (1·5%) | |
| 1st trimester | 7/7 (100·0%) | 73/83 (88·0%) | 47/51 (92·2%) | 26/32 (81·3%) | |
| 2nd trimester | 0 | 7/83 (8·4%) | 4/51 (7·8%) | 3/32 (9·4%) | |
| 3rd trimester | 0 | 1/83 (1·2%) | 0 | 1/32 (3·1%) | |
| Unknown | 0 | 2/83 (2·4%) | 0 | 2/32 (6·3%) | |
| Adverse pregnancy outcomes | |||||
| Any adverse outcome | 2 (0·6%) | 50 (0·9%) | 31 (0·9%) | 19 (0·9%) | |
| Preterm labour | 0 | 3 (0·1%) | 1 (<0·1%) | 2 (0·1%) | |
| High blood pressure | 0 | 6 (0·1%) | 4 (0·1%) | 2 (0·1%) | |
| Vaginal spotting or vaginal bleeding | 1 (0·3%) | 21 (0·4%) | 10 (0·3%) | 11 (0·5%) | |
| Abnormal fetal heart rate | 0 | 2 (<0·1%) | 1 (<0·1%) | 1 (<0·1%) | |
| Other pregnancy complications* | 1 (0·3%) | 30 (0·5%) | 17 (0·5%) | 13 (0·6%) | |
Data are n (%) or n/N (%). Participants were able to report multiple outcomes.
*
Included lower abdominal pain, reduced fetal movement, cramp, and vomiting.