IRCT2014012716376N1.

Trial name or title	Comparing two methods of cannula nasal with high flow and conventional FiO2 for successful weaning of preterm infants with respiratory distress from Nasal CPAP in Alzahra and Shahidbeheshti hospitals, Isfahan
Methods	RCT. Sample size 88
Participants	Preterm infants with respiratory distress syndrome (RDS) and gestational age of 28 to 37 weeks' who require NCPAP; being stable on NCPAP at FiO2 = 0.30 for 6 hours; no clinical sign of RDS such as tachypnoea, severe apnoea, intercostals retraction and nasal flaring.
Interventions	Intervention 1: Intervention group (Humidified High Flow Nasal Cannula group) who wean from NCPAP at FiO2= 0.30 and receive 2 L/min O2 via cannula nasal. Intervention 2: Control group: who are connected to the NCPAP at FiO2= 0.21 to achieve a stable condition for 24 hours.
Outcomes	Apnoea. Timepoint: from the time on the Nasal Continuous Positive Airway Pressure (NCPAP) until weaning from O2. Method of measurement: Observation Duration of need for respiratory support. Timepoint: from the time on the Nasal Continuous Positive Airway Pressure (NCPAP) till weaning from O2. Method of measurement: Observation
Starting date	20/04/2012
Contact information	Dr. Alireza Eshghi  ali_phd203@ yahoo.com
Notes	IRCT2014012716376N1