Fig. 7.

The effects of EMA401 and A3E on proliferation in primary GBM cultures. Primary GBM cultures TB43, TB48, GBM59, and GBM96 were treated with EMA401 (30 μM), A3E (10 μM), and TMZ (30 μM) in 1% serum and analyzed 9 d posttreatment with CCK8. Data shown are mean absorbance A450 values normalized to the untreated control (UC) ± SEM. Statistical significance was analyzed using one-way ANOVA with Dunnett’s multiple comparisons test between treated groups and untreated control. ***P ≤ 0.001, ****P ≤ 0.0001.