Table 1.
Compound | Antiprotozoal activity (IC50, μM)* against P. falciparum 3D7 |
---|---|
1 | 13.5 ± 0.8 |
2 | 20.9 ± 0.2 |
3 | 23.7 ± 2.4 |
4 | 43.3 ± 5.1 |
M1 | 31.0 ± 0.9 |
M2 | 36.7 ± 0.9 |
6 | 40.2 ± 1.1 |
7 | >50 |
8 | 25.5 ± 0.3 |
9 | >50 |
11 | 10.0 ± 0.4 |
Artemisinin† | 0.008 ± 0.0002 |
*All values represent the means ± SD based on three independent experiments of three replicates each (n = 9).
†Artemisinin was used as the positive control.