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. 2022 Aug 1;119(32):e2123379119. doi: 10.1073/pnas.2123379119

Table 1.

Antimalarial activity of xylomyrocins

Compound Antiprotozoal activity (IC50, μM)* against P. falciparum 3D7
1 13.5 ± 0.8
2 20.9 ± 0.2
3 23.7 ± 2.4
4 43.3 ± 5.1
M1 31.0 ± 0.9
M2 36.7 ± 0.9
6 40.2 ± 1.1
7 >50
8 25.5 ± 0.3
9 >50
11 10.0 ± 0.4
Artemisinin 0.008 ± 0.0002

*All values represent the means ± SD based on three independent experiments of three replicates each (n = 9).

Artemisinin was used as the positive control.