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. 2022 Aug 4;2022:4156966. doi: 10.1155/2022/4156966

Figure 1.

Figure 1

HNSCAT1 is downregulated in HNSC. (a) Pancancer analysis of RNA expression of linc01269 in TCGA database. (b) Expression of linc01269 in HNSC and normal samples. These data were acquired from GEPIA2 (http://gepia2.cancer-pku.cn). Significance was assessed by unpaired two-tailed Student's t-test. ∗p < 0.05. (c) Stage IV HNSC samples presented the lowest linc01269 expression level. The figure was generated on the GEPIA2 website (http://gepia2.cancer-pku.cn). Significance was assessed by unpaired two-tailed Student's t-test. ∗p < 0.05. (d, e) Elevated linc01269 expression was associated with favorable outcomes in terms of both (d) overall survival (log-rank p = 0.0091) and (e) disease-free survival (log-rank p = 0.005). (f, g) RACE assay for the identification of full-length linc01269. The novel transcript harbors a 166 bp extension in the 5′ terminus and a 303 bp extension in the 3′ terminus.