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. 2022 Aug 4;2022:6160701. doi: 10.1155/2022/6160701

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Copyright © 2022 Bo Wang et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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The administration of DPX reduced iron and ROS accumulation after ICH in mice. (a) Representative Perl's blue staining indicating iron accumulation in each group. Scale bars: 50 μm. (b) Semiquantification of iron accumulation from (a). n = 5 in each group; F(2, 12) = 61.52; ^∗∗∗p < 0.001 vs. Sham group; ^###p <0.001 vs. ICH group; one-way ANOVA, followed by Turkey's post hoc test. (c) Double staining of MBP (green) and DHE (red) demonstrating the ROS level in each group. Scale bars: 50 μm. (d) The percentage of ROS positive area from (e). n = 7 in Sham group, n = 6 in ICH group, n = 7 in ICH + DPX group; F (2, 17) = 44.08; ^∗∗∗p < 0.001 vs. Sham group; ^###p < 0.001 vs. ICH group; one-way ANOVA, followed by Turkey's post hoc test.