FIG. 1.
Restriction map and the predicted gene organization of the uvr operon of the 47.5-kb Tn5252. The EcoRI site at the right end is about 8.5 kb from the left end of the element. Relevant restriction sites are shown. Thin line, chromosomal DNA; box, transposon DNA; crosshatched box, the 4.5-kb DNA containing the uvr genes; black boxes, direct repeats of insertion sequence-like sequences. The location of the cat is shown. The vertical lines in the transposon DNA indicate EcoRI sites. Subclones derived from the 4.5-kb EcoRI fragment of DNA shown in the lower panel with relevant restriction endonuclease sites and a nested set of deletion derivatives obtained following exonuclease III and S1 treatments were used to determine the sequence data from both the strands. The directions and lengths of the potential ORFs are shown at bottom.