TABLE 2.
Effect of the uvr operon of Tn5252 on UV-induced mutagenesis
Strain | UV dose (J/m2) | % Survival | No. of cells per 108 survivors carrying the indicated mutationa
|
||
---|---|---|---|---|---|
Fusr | Optr | His+ | |||
S. pneumoniae | |||||
SP1311 | 0 | 100 | 0 | 0 | |
10 | 0.152 | 50 | 0 | ||
25 | 0.00059 | 40 | 40 | ||
SP1317 | 0 | 100 | 20 | 30 | |
10 | 11.56 | 310 | 4,420 | ||
25 | 3.4 | 6,220 | 113,000 | ||
E. coli | |||||
AB1157 | 0 | 100 | 0 | ||
5 | 72 | 18 | |||
10 | 48 | 52 | |||
25 | 15.5 | 189 | |||
RM1140 | 0 | 100 | 0 | ||
5 | 3 | 0 | |||
10 | 0.55 | 0 | |||
25 | 0.2 | 0 | |||
RM1140(pSE117) | 0 | 100 | 0 | ||
5 | 80 | 40 | |||
10 | 52 | 187 | |||
25 | 18.5 | 310 | |||
RM1140(pKM101) | 0 | 100 | 0 | ||
5 | 92 | 302 | |||
10 | 62 | 706 | |||
25 | 21 | 880 | |||
RM1140(pSJ142) | 0 | 100 | 0 | ||
5 | 87 | 160 | |||
10 | 60 | 264 | |||
25 | 29 | 950 | |||
RM1140(pAT29) | 0 | 100 | 0 | ||
5 | 5.1 | 0 | |||
10 | 0.47 | 0 | |||
25 | 0.17 | 0 |
Fusr, resistance to fusidic acid; Optr, resistance to optochin; His+, histidine prototrophic revertants.