Fig 1.

Schematic organization of SARS-CoV-2 genome and proteome. SARS-CoV-2 possesses a positive-sense single-stranded RNA (ssRNA) genome of nearly 30kb in size. The ssRNA is translated into a polypeptide which is further cleaved by viral proteases into individual proteins. ORF1a and ORF1b encode nonstructural proteins (nsp1-nsp16), the other ORFs encode structural proteins spike (S), membrane (M), envelope (E), and nucleocapsid (N). Accessory proteins are also encoded in the genome such as: ORF3, ORF6, ORF7, ORF8, and ORF10. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)