Table 4.
Prognostic factors for the overall survival in patients with pancreatic cancer.
| Characteristics | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | p-value | HR | 95% CI | p-value | |
| Sex (Male vs. Female) | 2.82 | 1.50–5.33 | 0.001 | 3.14 | 1.66–5.95 | 0.001 |
| Age (> 70 years) | 0.96 | 0.55–1.69 | 0.90 | |||
| Body mass index (< 22) | 1.01 | 0.91–1.10 | 0.98 | |||
| ASA classification 1 or 2 vs. 3 | 2.36 | 0.92–6.01 | 0.07 | |||
| Preoperative albumin (< 3.6 g/L) | 0.56 | 0.31–1.00 | 0.050 | |||
| CEA (> 3.6 ng/mL) | 1.66 | 0.92–2.99 | 0.09 | |||
| CA19-9 (> 52.0 U/mL) | 1.34 | 0.76–2.35 | 0.31 | |||
| GNRI (< 99) | 2.46 | 1.36–4.44 | 0.003 | 2.49 | 1.37–4.54 | 0.003 |
| Operation methods (PD or DP) | 2.58 | 1.32–5.01 | 0.005 | 2.32 | 1.17–4.61 | 0.02 |
| Postoperative complications | 1.62 | 0.90–2.92 | 0.11 | |||
| Stage I, II/ III, IV | 1.02 | 0.40–2.56 | 0.97 | |||
| Adjuvnt chemotherapy | 1.12 | 0.65–2.84 | 0.70 | |||
ASA, American Society of Anesthesiologists; GNRI, geriatric nutritional risk index; PD, pancreatoduodenectomy; DP, distal pancreatectomy.