Skip to main content
. 2022 Aug 11;12:329. doi: 10.1038/s41398-022-02096-5

Table 2.

CfB in selected EEG parameters for the Fz electrode at EoT.

MMN amplitude ASSRa (40 Hz stimulation) Resting state power in gamma band
Duration (µV) Frequency (µV) Duration + frequency (µV) Induced power (dB) Evoked power (dB) Phase-locking factor Absolute power (µV2) Relative power (%)
Total patients (N = 79)
Nb 47 46 47 37 57
Mean −0.02 0.17 −0.10 0.15 −0.09 −0.00 −0.02 −0.23
SEM 0.21 0.20 0.25 0.20 1.20 0.01 0.26 0.25
SD 1.41 1.33 1.70 1.20 7.27 0.07 1.93 1.88
Min −2.54 -3.21 −4.89 −1.87 −12.21 −0.13 −6.21 −11.52
Max 3.31 3.23 3.28 4.03 13.02 0.19 10.29 4.81
Placebo (N = 20)
Nb 12 10 15
Mean −0.22 0.68 0.29 0.26 0.79 0.01 −0.76 −0.46
SEM 0.40 0.47 0.61 0.45 2.25 0.03 0.28 0.25
SD 1.38 1.62 2.11 1.42 7.13 0.08 1.10 0.96
Min −2.18 −2.17 -3.82 −1.87 −10.91 −0.07 −3.97 −3.20
Max 1.70 2.94 3.28 3.41 11.83 0.19 0.83 1.23
Iclepertin 10 + 25 mg (N = 35)
Nb 21 15 26
Mean −0.01 0.33 -0.08 0.01 −2.09 −0.01 0.24 −0.43
SEM 0.30 0.23 0.40 0.20 1.78 0.02 0.50 0.47
SD 1.36 1.05 1.84 0.76 6.90 0.06 2.56 2.41
Min −2.54 −1.59 −4.89 −1.53 −12.21 −0.13 −6.21 −11.52
Max 1.72 3.23 2.79 0.99 12.33 0.09 10.29 2.15

ASSR auditory steady-state response, CfBchange from baseline; EEG electroencephalography; EoT end of treatment, MMN mismatch negativity, SD standard deviation; SEM standard error of the meanASSR, auditory steady-state response; CfB change from baseline, EEG electroencephalography, EoT end of treatment, MMN mismatch negativity, SD standard deviation, SEM standard error of the mean.

aBaseline-corrected.

bNumber of patients with analyzable data for each EEG parameter.