Table 2. Univariate and multivariate Cox regression analysis of variables associated with overall survival for resected stage IIIa-N2 NSCLC patients who have received adjuvant chemotherapy before PSM.
| Characteristics | Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | ||
| Age (years) | |||||
| <65 | Reference | Reference | |||
| ≥65 | 1.342 (1.225–1.470) | <0.001 | 1.330 (1.214–1.457) | <0.001 | |
| Sex | |||||
| Female | Reference | Reference | |||
| Male | 1.249 (1.142–1.366) | <0.001 | 1.242 (1.133–1.361) | <0.001 | |
| Grade | |||||
| I–II | Reference | Reference | |||
| III–IV | 1.172 (1.072–1.282) | <0.01 | 1.147 (1.048–1.255) | 0.0124 | |
| Histology | |||||
| Adenocarcinomas | Reference | Reference | |||
| Squamous cell neoplasms | 1.195 (1.064–1.343) | 0.0119 | 1.180 (1.047–1.331) | 0.0229 | |
| Others | 1.200 (1.047–1.376) | 0.0277 | 1.228 (1.070–1.409) | 0.0142 | |
| AJCC T | |||||
| T1 | Reference | Reference | |||
| T2 | 1.271 (1.159–1.394) | <0.001 | 1.269 (1.157–1.393) | <0.001 | |
| Laterality | |||||
| Left | Reference | ||||
| Right | 0.930 (0.850–1.018) | 0.186 | |||
| LNR | |||||
| <0.31 | Reference | Reference | |||
| ≥0.31 | 1.607 (1.469–1.758) | <0.001 | 1.663 (1.519–1.821) | <0.001 | |
| PORT | |||||
| No | Reference | ||||
| Yes | 0.936 (0.856–1.024) | 0.227 | |||
NSCLC, non-small cell lung cancer; PSM, propensity score matching; HR, hazard ratio; AJCC, American Joint Committee on Cancer; LNR, lymph node ratio; PORT, postoperative radiotherapy.