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. 2022 Aug 12;12(1):30. doi: 10.1007/s13659-022-00352-1

Table 2.

Effect of dry bearberry leaves extracts on HOMA-IR in a model of insulin-resistance induced by dexamethasone injections in rats

Indices Time period
Initial 5 weeks 7 weeks/experimental groups
IC Dex IC Dex Dex_PE50 Dex_PE50_cys Dex_cys Dex_met Dex_arph
Glucose, mmol/L 4.15 ± 0.28 4.03 ± 0.41 5.93 ± 0.63* 3.95 ± 0.27 7.58 ± 0.91* 5.81 ± 0.54*/# 5.37 ± 0.49# 6.01 ± 0.47* 5.33 ± 0.31*/# 6.11 ± 0.47*
IRI, pmol/L 73 ± 7 72 ± 8 105 ± 8* 74 ± 9 121 ± 15* 91 ± 9* 82 ± 7*/# 90 ± 9* 71 ± 6*/# 95 ± 10
HOMA 1.9 ± 0.6 1.8 ± 0.6 4.0 ± 0.8*/# 1.7 ± 0.6 5.9 ± 0.9 3.4 ± 0.6*/# 2.8 ± 0.3# 3.5 ± 0.2 2.4 ± 0.2 3.7 ± 0.4

Each value represents the mean ± standard error (n = 6)

*Indicates significant difference relative to IC group (p ≤ 0.05)

#Indicates significant difference relative to Dex group (p ≤ 0.05)