Table 4.

Morphometric parameters of pancreas incretory apparatus in insulin resistant rats and after 2 weeks of treatment with dry bearberry leaves extracts

Experimental groups	Optical density (total Li number in microsample)	Li profile—the number of beta cells in the islet (distribution of pancreatic islets by beta cell content)									Functional index (β/α cells)
		Small			Medium			Large
		Number	%	Perimeter, µm	Number	%	Perimeter, µm	Number	%	Perimeter, µm
IC	19.83 ±  0.71	4.30 ±  0.81	21.77 ±  2.31	278.35 ±  30.23	13.33 ±  0.82	67.16 ±  2.85	861.31 ±  45.63	2.10 ±  0.75	10.83 ±  2.04	1935.13 ±  53.51	4.83 ±  0.41
Dex	16.50 ±  0.56*	5.83 ±  0.75*	35.35 ±  4.75*	139.55 ±  12.57*	8.33 ±  1.03*	50.61 ±  6.94*	718.11 ±  57.25*	2.33 ±  1.21	13.81 ±  4.91	2477.13 ±  385.37*	2.73 ±  0.44
Dex_PE50	17.72 ±  0.54#	5.79 ±  0.48	34.33 ±  1.54	262.80 ±  34.46#	8.83 ±  1.32	51.85 ±  6.17	809.75 ±  57.47#/&	2.16 ±  0.75	13.82 ±  3.14	1873.80 ±  85.55#	3.01 ±  0.12
Dex_PE50_cys	18.33 ±  0.51#	4.67 ±  0.51#	22.43 ±  2.62#	268.90 ±  37.08#	11.16 ±  0.98#	60.91 ±  5.19#	852.50 ±  55.87#	2.66 ±  0.51	14.52 ±  2.87	1767.85 ±  55.69*/#	3.26 ±  0.53
Dex_cys	16.95 ±  0.67*&	5.67 ±  0.54*	33.45 ±  0.46	157.48 ±  27.76*/&	9.74 ±  0.72*&	57.46 ±  4.67	735.51 ±  40.40*/&	2.03 ±  0.61	11.97 ±  3.21	1911.71 ±  62.45#	2.54 ±  0.23
Dex_arph	17.33 ±  1.03	5.83 ±  0.40	33.67 ±  1.21	232.20 ±  38.30*/#	9.33 ±  0.81	53.87 ±  3.86	802.66 ±  50.18&	2.16 ±  0.98	12.45 ±  5.24	1882.55 ±  71.19#	2.93 ±  0.39
Dex_met	18.66 ±  0.81#	4.66 ±  0.50#	24.97 ±  2.19#	293.63 ±  26.56#	11.50 ±  0.54#	61.65 ±  3.07#	880.50 ±  51.54#	2.50 ±  0.83	13.36 ±  4.50	1966.96 ±  82.12#	3.74 ±  0.38

Each value represents the mean ± standard error (n = 6)

^*Indicates significant difference relative to IC group (p ≤ 0.05)

^#Indicates significant difference relative to Dex group (p ≤ 0.05)

^&Indicates significant difference relative to Dex_PE_cys group (p ≤ 0.05)