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. 2022 Jul 29;13:951214. doi: 10.3389/fimmu.2022.951214

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Copyright © 2022 Mak, Li, Huang, Wu, Huang, He and Zhang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Identification of CAFs subtypes in GC. (A) Consensus matrix heatmap defining two clusters (k = 2) and their correlation area. (B) Univariate analysis indicating 18 CAFs-related genes corelated with the OS time. (C) GSVA of biological pathways between two distinct subtypes. (Red and blue represent activated and inhibited pathways, respectively). (D) Differences in clinicopathologic features and expression levels of CAFs-related genes between the two distinct subtypes. (E) The 22 infiltrating immune cell types in the two GC subtypes. **P<0.01, ***P<0.001.