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. 2022 Jul 29;13:951214. doi: 10.3389/fimmu.2022.951214

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Copyright © 2022 Mak, Li, Huang, Wu, Huang, He and Zhang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Characteristic in gene mutation and relationship of CAFS-score with MSI and CSC index. (A, B) Significantly mutated genes in the mutated GC samples of the high and the low risk groups, respectively. Mutated genes (rows, top 20) are ordered by mutation rate; samples (columns) are arranged to emphasize mutual exclusivity among mutations. The right shows mutation percentage, and the top shows the overall number of mutations. The color-coding indicates the mutation type. (C) The TMB of two differen risk subgroups. (D) Relationships between CAFS-score and TMR in three gene subtypes. (E) Relationships between CAFS-score and CSC index. (F, G) Relationships between CAFS-score and MSI.