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. 2022 Jul 29;13:922312. doi: 10.3389/fendo.2022.922312

Table 3.

Association between demographics/characteristics and the risk of metabolic syndrome (N = 2,416).

Univariate analysis Multivariable analysis a
Variable OR (95% CI) p OR (95% CI) p
Female sex 1.05 (0.89–1.24) 0.588
Age, years 1.028 (1.022–1.034) <0.001 1.02 (1.01–1.03) <0.001
Education level, years 0.93 (0.91–0.94) <0.001 0.96 (0.94–0.98) <0.001
Vegetable intake ≥3 portions per day 0.86 (0.73–1.02) 0.085 1.19 (0.92–1.55) 0.189
Fruit intake ≥2 portions per day 0.79 (0.67–0.93) 0.004 0.82 (0.63–1.05) 0.114
Water intake ≥1,500 cc per day 1.02 (0.87–1.20) 0.815
Irregular exercise 1.187 (0.998–1.412) 0.052 1.12 (0.93–1.35) 0.227
Smoking 1.12 (0.91–1.38) 0.297
Betel nut chewing 1.57 (1.18–2.08) 0.002 1.41 (1.05–1.90) 0.021
Alcoholic drinking 1.04 (0.80–1.35) 0.779
AST, U/L 1.02 (1.01–1.03) <0.001
ALT, U/L 1.022 (1.016–1.028) <0.001
ALT/AST >1 b 2.03 (1.69–2.44) <0.001 2.63 (2.15–3.21) <0.001
HBV and HCV status
 None Reference Reference
 HBV only 0.66 (0.50–0.88) 0.005 0.70 (0.52–0.95) 0.021
 HCV only 1.314 (1.028–1.679) 0.029 1.03 (0.79–1.33) 0.836
 HBV and HCV 2.04 (0.93–4.51) 0.077 1.52 (0.67–3.43) 0.312

OR, odds ratio; CI, confidence interval; BMI, body mass index; AST, aspartate aminotransferase; ALT, alanine aminotransferase; eGFR, estimated glomerular filtration rate; HBV, hepatitis B virus; HCV, hepatitis C virus.

a

Those variables whose significant levels were less than 0.15 were further included in the multivariable logistic regression model.

b

Among the indicators of liver function (AST, ALT, ALT/AST ratio, and ALT/AST ratio >1), ALT/AST ratio >1 was chosen in the multivariable model to prevent the problem of multicollinearity.