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. 2022 Jul 29;13:928593. doi: 10.3389/fimmu.2022.928593

Figure 8.

Figure 8

Nanoparticles delivery of miR-144/451 ameliorates DSS-induced colitis in KO mice. WT and miR-144/451 KO mice were treated with 2.5% DSS and intraperitoneally injected with chitosan-plasmid nanoparticles daily. Changes in body weight (A). Disease activity index of colitis (B). Morphology of colons, and bars represent the length of colons (C). Histological sections (40 ×)and pathological scores (D). *WT-Control vs. WT-miR-144/451, #KO-Control vs. KO-miR-144/451, n = 5. Ns. no significance, *p<0.05.