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. 2022 Aug 4;2022(3):29. doi: 10.5339/qmj.2022.35

Table 1.

Mean change in serum vitamin D after four types of replacement therapies.

Serum vitamin D ng/ml-Changes (after the first dose) Difference in mean compared to the reference Effect size (Cohen's d) compared to the reference P value for difference in mean compared to the reference

Range Mean SD SE N category category category

Type of vitamin D prescribed

vitamin D2 injection (-16 to 50) 3.2 0.51 0.33 411 Reference

vitamin D3 injection (-17 to 48) 9.3 0.69 0.49 454 6.1 0.69  < 0.001

vitamin D2 injection + D2 tablet (-18 to 47) 5.5 0.32 0.18 1585 2.3 0.32  < 0.001

vitamin D3 injection + D2 tablet (-18 to 47) 8.8 0.94 0.27 997 5.6 0.94  < 0.001

P (ANOVA) <  0.001

P (Paired t-test) for each of the four treatments < 0.001