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NSI-189 reverses deficits in synaptic plasticity and hippocampal volume. (a) Hippocampal CA3 volume. Western blot analysis for (b) NeuN, (c) synaptophysin, and (d) PSD-95 proteins (C: control, Z: ZDF, and Z+N: ZDF+NSI-189 groups). ∗p < 0.05, ∗∗p < 0.01, one-way ANOVA followed by Holm-Sidak's post hoc test against the ZDF+vehicle group. N = 8-10 animals per group, due to the quality of bands. Data are mean ± SEM.
