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. 2022 Jul 29;10:961509. doi: 10.3389/fped.2022.961509

Figure 3.

Figure 3

Forest plot of comparison of CPAP plus minimally invasive surfactant administration via thin catheter or laryngeal mask airway (LMA) vs. CPAP only. The outcome of interest was CPAP failure as determined by need for intubation. These minimally invasive techniques are associated with a 47% risk reduction in CPAP failure (142144, 150).