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. 2022 Jul 19;8(8):e10003. doi: 10.1016/j.heliyon.2022.e10003

Table 6.

Descriptors values for newly designed pyrazole carbohydrazide derivatives and their predicted anticancer activity against skin cancer cell line - B16F10 calculated according to the developed 2D-QSAR mathematical model.

New Designed Molecules SlogP_VSA5 PEOE_VSA+0 Zagreb VSA_Other SMR_VSA1 SMR_VSA7 PIC50
Image 6 41.6416 284.6402 208 19.6490 111.2582 291.8642 9.35
Image 7 41.6416 286.8487 210 19.6490 111.2582 291.8642 9.33
Image 8 41.6416 329.8571 208 19.6490 85.8730 325.1902 9.28
Image 9 60.5100 327.6486 208 19.6490 85.8730 325.1902 9.06
Image 10 60.5100 296.0316 204 19.6490 85.8730 325.1902 8.91