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. 2022 Jul;10(14):785. doi: 10.21037/atm-22-3332

Table 3. Univariable and multivariable analysis of association between clinicopathological factors and OS.

Variable Univariable analysis Multivariable analysis
HR 95% CI P value HR 95% CI P value
Age, years 1.03 0.99–1.08 0.1496
Gender (male vs. female) 1.64 0.60–4.52 0.3381
Presentation (primary vs. recurrence) 0.21 0.07–0.66 0.0071 0.17 0.04–0.68 0.0122
CR vs. TRL 2.67 0.76–9.40 0.1262
Hemoglobin, g/dL (≥12.75 vs. <12.75)* 0.40 0.14–1.13 0.0846
Albumin, g/dL (≥3.9 vs. <3.9)* 0.24 0.07–0.82 0.0234 0.5771
Tumor size, cm (≥21 vs. <21)* 0.89 0.34–2.32 0.8185
No. of tumors (unifocal vs. multifocal) 0.39 0.14–1.12 0.0793
Resected organs
   1 vs. none 3.21 0.62–16.61 0.1649
   2 vs. none 7.37 1.56–34.78 0.0116 0.1478
   ≥3 vs. none 5.78 0.81–41.22 0.0798
Estimated blood loss, mL 1.00 1.00–1.00 <0.0001 1.00 1.00–1.00 <0.0001
FNCLCC grade
   II + III vs. I 6.85 1.86–25.22 0.0038 0.1530
   III vs. I + II 7.57 2.31–24.80 0.0008 6.87 2.06–22.93 0.0017
Histologic subtype
   DDLPS vs. WDLPS 2.35 0.70–7.85 0.1647
CD classification (<3 vs. ≥3) 0.41 0.14–1.17 0.0845
Length of hospital stay, days 1.03 1.01–1.05 0.0008 0.1242

*, median value. OS, overall survival; HR, hazard ratio; CI, confidence interval; CR, complete resection; TRL, total (ipsilateral) retroperitoneal lipectomy; FNCLCC, Fédération Nationale des Centres de Lutte Contre le Cancer; DDLPS, dedifferentiated liposarcoma; WDLPS, well-differentiated liposarcoma; CD, Clavein-Dindo.