Table 1. Comparison of the characteristics of the IPF patients and healthy controls.
Characteristics | Controls (n=20) | IPF (n=83) | P value |
---|---|---|---|
Age, years | 59.55±13.82 | 60.47±10.39 | 0.783 |
BSA | 1.61±0.15 | 1.69±0.16 | 0.065 |
Male | 13 (65.00) | 54 (65.06) | 0.399 |
Smoker | 10 (50.00) | 40 (48.19) | 0.961 |
LDH, U/L | 145 (177, 241) | 146 (203, 307) | 0.177 |
CRP, mg/L | 5.00 (6.00, 7.00) | 17.00 (23.00, 42.00) | <0.001 |
CD4 T cell, 109/L | 0.49 (0.25, 0.80) | 0.28 (0.14, 0.47) | 0.036 |
CD8 T cell, 109/L | 0.28 (0.20, 0.40) | 0.23 (0.16, 0.41) | 0.640 |
NK cell, 109/L | 0.30 (0.10, 0.47) | 0.22 (0.13, 0.40) | 0.726 |
B cell, 109/L | 0.19 (0.11, 0.27) | 0.20 (0.11, 0.28) | 0.726 |
sST2, ng/mL | 22.25 (11.27, 56.00) | 67.50 (12.38, 124.50) | 0.026 |
The data are shown as n (%), mean ± SD, and median (interquartile range). IPF, idiopathic pulmonary fibrosis; BSA, body surface area; LDH, lactate dehydrogenase; CRP, C-reactive protein; NK, natural killer; sST2, soluble suppression of tumorigenicity-2.