Table 4c.
Average cytokine concentration at Day0 (pre-vaccination) and Day56 (post second-dose).
| Formulation | Average Interferon-gamma concentration (pg/mL) |
Average IL-4 concentration (pg/mL) |
||||||
|---|---|---|---|---|---|---|---|---|
| D-0 Null | D-0 Active | D-56 Null | D-56 Active | D-0 Null | D-0 Active | D-56 Null | D-56 Active | |
| A | 2·24 | 7·95 | 1·75 | 14·01 | 1·45 | 1·63 | 1·31 | 1·36 |
| B | 2·04 | 3·73 | 1·91 | 31·42 | 3·77 | 3·72 | 2·73 | 3·19 |
| C | 1·99 | 5·59 | 2·08 | 22·03 | 1·06 | 1·69 | 1·02 | 1·60 |
| D | 2·59 | 3·02 | 1·87 | 23·03 | 1·07 | 1·23 | 0·89 | 1·22 |
D-0: Day0; D-56; Day56; IL-4: Interleukin 4; pg/mL: picogram per milliliter.
Note: Cytokine measured in the supernatants of whole-blood samples incubated in tubes coated with SARS-COV-2 peptides (Active) and without coating (Null) for a subset of subjects from all four cohorts.