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Histological and immunohistochemical images of Merkel cell carcinoma. A: Hematoxylin and eosin staining showed “small round blue cell tumor”; B: Immunohistochemical staining for keratin 20 showed perinuclear dot-like staining. C: Immunohistochemical staining for KI-67 showed a very high proliferative index; D: Immunohistochemical staining for synaptophysin showed the staining of the neuroendocrine granules in the cytoplasm of cells. Magnification, × 400.
