Table 1. Characteristics of Tamoxifen and Docetaxel/Paclitaxel Users.
Characteristic | Tamoxifen | Docetaxel/paclitaxel |
---|---|---|
Epiphora | ||
No. | 16 395 | 1824 |
Age, y, mean (SD) | 54.6 (12.8) | 62.1 (12.7) |
Follow-up, y, mean (SD) | 3.5 (3.1) | 2.0 (1.9) |
Events, No. | 45 | 20 |
Rate | 7.9/10 000 person years | 55.6/10 000 person years |
Keratoconjunctivitis, % | 0.05 | 0.11 |
Dry eye syndrome, % | 0.29 | 2.25 |
Keratitis, % | 2.07 | 3.95 |
Blepharitis, % | 2.16 | 4.61 |
Eyelid malposition, % | 0.55 | 1.35 |
Cystoid macular edema | ||
No. | 16 524 | 1909 |
Age, y, mean (SD) | 54.6 (12.8) | 62.5 (12.8) |
Follow-up, y, mean (SD) | 3.5 (3.1) | 2.0 (1.9) |
Events, No. | 96 | 13 |
Rate | 16.8/10 000 person years | 34.8/10 000 person years |
Cataract, % | 0.6 | 2.1 |
Diabetes, % | 8.0 | 14.3 |
Optic neuropathy | ||
No. | 16 395 | 1824 |
Age, y, mean (SD) | 54.6 (12.8) | 62.5 (12.8) |
Follow-up, y, mean (SD) | 3.5 (3.1) | 2.0 (1.9) |
Events, No. | 7 | 4 |
Rate | 1.2/10 000 person years | 10.6/10 000 person years |
Hypertension, % | 6.0 | 38.2 |
Diabetes, % | 9.9 | 17.4 |
Coronary artery disease, % | 5.7 | 18.6 |