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. 2022 Jul 29;13:932722. doi: 10.3389/fimmu.2022.932722

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Copyright © 2022 Dong, Mu, Kong, Qin, Zhou, Wang, Cheng, Luo, Ai and Xu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The viral load and survival rate of gibel carp after challenge with CyHV-2. (A) The histogram showed loads of CyHV-2 in different tissues at 4 dpc (n = 6 fish per group). ns, not significant, *P < 0.05, ***P < 0.001, one-way ANOVA with Bonferroni correction. Data are representative of three different independent experiments (mean ± SEM). (B) The cumulative mortalities of gibel carp challenged with CyHV-2. Statistical differences were evaluated by log-rank (Mantel-Cox) test. (C) Efficacy of yeast vaccine in gibel carp under laboratory conditions. RPS, Relative survival rate = (1 - the ratio of mortality percent in the vaccine group or booster vaccine group to in the control group) × 100%.