Table 2.
Donor/replicate information of all HSPC experiments
| Replicate | Donor ID (sex) | sgRNA | Appearance in paper | Biological replicates, # (mice, #) |
|---|---|---|---|---|
| TERT exon 4 editing | ||||
| 1 | ROO3450 (male) | Synthetic |
Figure 4, supplemental Figure 4 |
1 (male) |
| 2 | ROO3716 (female) | Synthetic |
Figure 4, supplemental Figure 4 |
1 (male) |
| TIN2 exon 6 editing | ||||
| 1 | ROO3056 (female) | Synthetic |
Figure 5, supplemental Figure 8 |
3 (1 male, 2 female) |
| 2 | ROO3056 (female) | In vitro–transcribed | 3 (1 male, 2 female) | |
| TERT exon 9 editing | ||||
| 1 | ROO3450 (male) | Synthetic | Supplemental Figure 7 | 1 (male) |
| TIN2 exon 2 editing | ||||
| 1 | ROO3446 (female) | Synthetic |
Figure 6A-B, supplemental Figure 9A-C |
2 (1 male, 1 female) |