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. 2022 Jul 29;12:944248. doi: 10.3389/fonc.2022.944248

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Copyright © 2022 Liu, Hong, Qiu, Li, Liu, Zhu, Lai, Chen, Yang, Xu and Fang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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T-cell subsets of CB, PB, and PB (patient) groups. (A) Flow cytometry analysis of TN, TCM, TEM, and TEMRA in the three groups of T cells. Right upper quadrant: naive T (CD45RA+CCR7+), left upper quadrant: TCM (CD45RA-CCR7+), left lower quadrant: TEM (CD45RA-CCR7-), and right lower quadrant: TEMRA (CD45RA+CCR7-). (B) TN, TCM, TEM, and TEMRA in the three groups of T cells. (C) Proportion of Tregs in the three groups of T cells. (D) Flow cytometry analysis of Tregs (CD4+CD25+CD127-). TN, Naive T cell; TCM, Central memory T cell; TEM, effector memory T cell; TEMRA, Terminal effector T cell; Treg, regulatory T cell. *p < 0.05, **p < 0.01, ***p < 0.001.