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Copy number alterations and mutation profiles of ctDNA. (A) Heatmap of genomic alterations identified in tumors and plasma counterparts. TF, tumor fraction; HGSC, high-grade serous carcinoma; LGSC, low-grade serous carcinoma; EOC, endometrioid ovarian cancer; CC, clear cell. Stars represent cases with at least one tumor alteration identified in plasma. (B) Upset chart showing the comparison of single-nucleotide variants identified using WES versus t-NGS.
