Figure 8.

Probiotic CM beneficially regulates several processes in macrophage foam cell formation. Dil‐oxLDL uptake (A‐B), cholesterol efflux (C‐D), LY uptake (E) and phagocytosis (F) was carried out in THP‐1 macrophages (A, C, E‐F) or HMDM (B, D) treated with vehicle or CM from Lab4 (8 µg mL^‐1) or CUL66 (5 µg mL^‐1) as described in Section 4. Data are mean ± SEM from three independent experiments with values from vehicle‐treated cells arbitrarily assigned as 100%. Statistical analysis was performed using a one‐way ANOVA with Dunnett (2‐sided) post‐hoc test (A‐E) or Dunnett T3 post‐hoc test (F) (*p < 0.05, **p < 0.01 and ***p < 0.001).