Figure 10.

Probiotic CM modulates proliferation and migration of HASMC. The effect of vehicle or CM from Lab4 (8 µg mL^‐1) or CUL66 (5 µg mL^‐1) on cell proliferation and viability at day 7 (A and B, respectively) or PDGF‐induced migration (C) was determined as described in Section 4. For migration assays (C), cells incubated with the vehicle in the absence of PDGF were included for comparative purposes. Data are presented as mean ± SEM from three independent experiments with values from vehicle‐treated cells arbitrarily assigned as 100% (A‐B) or 1 (C). Statistical analysis was performed using a one‐way ANOVA with Dunnett (2‐sided) post‐hoc test (p < 0.001).